Some cleavage of lamin b may occur in the absence of caspase 3 whereas parp 1 another nuclear protein seems to be cleaved regardless of caspase 3. Caspase 9 belongs to a family of caspases cysteine aspartic proteases involved in apoptosis and cytokine. The lamins are type v intermediate filaments which can be categorized as either a type lamin a c or b type lamin b 1 b 2 according to homology of their dna sequences biochemical properties and cellular localization during the cell cycle.
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